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Department of Chemistry and Biochemistry
Freiestrasse 3
CH-3012 Berne

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Welcome


We are investigating post-transcriptional gene regulation in mammalian cells. In particular, we try to decipher the molecular mechanism and the biological and medical implications of nonsense-mediated mRNA decay (NMD). NMD is an important mRNA quality control process that recognizes and degrades mRNPs that fail to properly terminate translation, but also regulates expression levels of many physiological mRNAs.

Detailed Research Summary

 

NMD

   
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